SCHEMBL468916

SCHEMBL468916

COC(=O)C(CCC(N)=O)NC(C)=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 1/20 0.47
CNR2 P34972 2/20 0.40
CNR1 P21554 1/20 0.40
CHRM2 P08172 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM1 P11229 1/20 0.40
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA9 Q16790 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ALOX15 P16050 2/20 0.37
BLM P54132 2/20 0.37
KDM4E B2RXH2 1/20 0.37
MAPT P10636 1/20 0.37
THRB P10828 1/20 0.37
NFKB1 P19838 1/20 0.37
PTGS2 P35354 1/20 0.37
THPO P40225 1/20 0.37
RECQL P46063 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19177135 1.00 FOLH1 (0.47) FOLH1CNR2CNR1CHRM2CHRM4
SCHEMBL468918 1.00 FOLH1 (0.47) FOLH1CNR2CNR1CHRM2CHRM4
SCHEMBL21638032 0.91 FOLH1 (0.56) FOLH1CNR2CNR1CHRM2CHRM4
SCHEMBL468757 0.86 L3MBTL1 (0.54) FOLH1CHRM2CHRM4CHRM1L3MBTL1
SCHEMBL468758 0.86 L3MBTL1 (0.54) FOLH1CHRM2CHRM4CHRM1L3MBTL1
SCHEMBL468851 0.84 FOLH1 (0.38) FOLH1CHRM2CHRM4CHRM1CA2
SCHEMBL468852 0.84 FOLH1 (0.38) FOLH1CHRM2CHRM4CHRM1CA2
SCHEMBL27846693 0.84 L3MBTL1 (0.45) FOLH1CNR2CNR1CA12CA1
SCHEMBL27846690 0.84 L3MBTL1 (0.45) FOLH1CNR2CNR1CA12CA1
SCHEMBL12064029 0.84 SMN1; SMN2 (0.45) FOLH1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE42902-E1 N-acetyl aldosamines, N-acetylamino acids and related N-acetyl compounds and their topical use TRISTRATA, INC. (US) 2011-11-08 US claimed
WO-2006119283-A2 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J (US) 2006-11-09 WO claimed
US-20060251597-A1 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J 2006-11-09 US claimed
US-20230026277-A1 COMPOSITION FOR PREVENTION, ALLEVIATION, OR TREATMENT OF RESPIRATORY DISEASE MICROX CO., LTD. (KR) 2023-01-26 US disclosed
US-20230026277-A1 COMPOSITION FOR PREVENTION, ALLEVIATION, OR TREATMENT OF RESPIRATORY DISEASE MICROX CO., LTD. (KR) 2023-01-26 US disclosed
CN-114760995-A Composition for preventing, alleviating or treating respiratory diseases 微艾克斯有限公司 2022-07-15 CN disclosed
WO-2021107547-A1 COMPOSITION FOR PREVENTION, ALLEVIATION, OR TREATMENT OF RESPIRATORY DISEASE 단디바이오사이언스 주식회사 2021-06-03 WO disclosed
WO-2006119283-A2 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J (US) 2006-11-09 WO disclosed
US-20060251597-A1 ANTI-ODOR COMPOSITIONS AND THERAPEUTIC USE YU RUEY J 2006-11-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230026277-A1 COMPOSITION FOR PREVENTION, ALLEVIATION, OR TREATMENT OF RESPIRATORY DISEASE RELA, CSNK2A1, CSNK1G1 FOLH1 4044/4885CNR2 2554/4885CNR1 2540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.