Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD4 | P21917 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4693286 | 0.94 | TP53 (0.45) | MALT1TP53MAPTDRD2DRD4 | |
| SCHEMBL4690539 | 0.88 | TP53 (0.45) | MALT1TP53MAPTDRD2DRD4 | |
| SCHEMBL4691527 | 0.87 | DRD2 (0.47) | TP53DRD2DRD4DRD3KMT2A | |
| SCHEMBL4693056 | 0.87 | TP53 (0.44) | MALT1TP53MAPTKMT2ALMNA | |
| SCHEMBL4690604 | 0.87 | TP53 (0.44) | MALT1TP53MAPTDRD2DRD4 | |
| SCHEMBL4689933 | 0.85 | MALT1 (0.43) | MALT1TP53MAPTLMNAALDH1A1 | |
| SCHEMBL4695194 | 0.85 | TP53 (0.42) | MALT1TP53MAPTDRD2DRD4 | |
| SCHEMBL5662686 | 0.85 | MALT1 (0.50) | MALT1TP53MAPTDRD2DRD4 | |
| SCHEMBL4693136 | 0.85 | MAPT (0.46) | MALT1TP53MAPTKMT2ALMNA | |
| SCHEMBL4695971 | 0.85 | LMNA (0.50) | TP53MAPTKMT2ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |