Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 2/20 | 0.47 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.42 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | XIAP | P98170 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 2/20 | 0.39 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 4/20 | 0.39 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | LAP3 | P28838 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.37 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4047960 | 0.88 | GRIN2B (0.48) | F2CSNK1EEPHX1GRIN2BANPEP | |
| SCHEMBL14253003 | 0.88 | GRIN2B (0.48) | F2CSNK1EEPHX1GRIN2BANPEP | |
| SCHEMBL5805296 | 0.88 | GRIN2B (0.48) | F2CSNK1EEPHX1GRIN2BANPEP | |
| Hydrochloric Acid SCHEMBL6111346 | 0.87 | GRIN2B (0.47) | F2CSNK1EEPHX1GRIN2BANPEP | |
| SCHEMBL4692517 | 0.85 | ANPEP (0.49) | F2CSNK1EEPHX1GRIN2BANPEP | |
| SCHEMBL5930121 | 0.85 | ANPEP (0.52) | F2CSNK1EEPHX1GRIN2BANPEP | |
| Hydrochloric Acid SCHEMBL5216767 | 0.84 | ANPEP (0.48) | F2CSNK1EEPHX1GRIN2BANPEP | |
| SCHEMBL4693744 | 0.84 | ANPEP (0.54) | F2CSNK1EGRIN2BANPEPERAP2 | |
| SCHEMBL4695118 | 0.84 | ANPEP (0.54) | F2CSNK1EGRIN2BANPEPERAP2 | |
| SCHEMBL5720870 | 0.84 | ANPEP (0.54) | F2CSNK1EGRIN2BANPEPERAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1692143-B1 | TRICYCLIC INDOLE HYDROXYETHYLAMINE DERIVATIVES AND THEIR USE IN THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2008-11-12 | — | — | EP | disclosed |