SCHEMBL4689979

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10906216	0.80	CES1 (0.52)	CES1CES2AKR1B1TDP1L3MBTL1
	SCHEMBL10433055	0.74	HMGCR (0.32)	CYP2C19TSHRHIF1A
	Methyl Alcohol SCHEMBL11054071	0.72	CES1 (0.64)	CES1CES2AKR1B1TDP1L3MBTL1
	SCHEMBL6520274	0.72	CES1 (0.40)	CES1CES2AKR1B1TDP1L3MBTL1
	SCHEMBL77563	0.72	CES1 (0.70)	CES1CES2AKR1B1TDP1L3MBTL1
	SCHEMBL11378361	0.72	CES1 (0.52)	CES1CES2AKR1B1TDP1L3MBTL1
	SCHEMBL1033376	0.72	CES1 (0.59)	CES1CES2AKR1B1TDP1L3MBTL1
	SCHEMBL1529438	0.72	MCL1 (0.55)	CES1CES2AKR1B1TDP1L3MBTL1
	SCHEMBL5784144	0.71	SLC6A2 (0.52)	ALDH1A1CYP2C19CYP3A4CYP2C9HIF1A
	Benzene SCHEMBL27747096	0.71	CES1 (0.56)	CES1CES2AKR1B1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.