SCHEMBL4690053

SCHEMBL4690053

COc1ccc(/C=C(\C#N)c2ccc(Cl)cc2)cc1OC

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.62
SMN1; SMN2 Q16637 1/20 0.62
HIF1A Q16665 1/20 0.62
EGFR P00533 1/20 0.62
PDGFRB P09619 1/20 0.62
PDGFRA P16234 1/20 0.62
NQO1 P15559 1/20 0.58
NQO2 P16083 1/20 0.58
MAPT P10636 2/20 0.55
HTT P42858 2/20 0.55
NPSR1 Q6W5P4 2/20 0.55
KDM4E B2RXH2 1/20 0.55
TUBB4A P04350 3/20 0.55
TUBB P07437 3/20 0.55
TUBA3C P0DPH7 3/20 0.55
TUBA1B P68363 3/20 0.55
TUBA4A P68366 3/20 0.55
TUBB4B P68371 3/20 0.55
TUBB3 Q13509 3/20 0.55
TUBB2A Q13885 3/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4686892 1.00 RECQL (0.62) RECQLSMN1; SMN2HIF1AEGFRPDGFRB
SCHEMBL4686894 1.00 RECQL (0.62) RECQLSMN1; SMN2HIF1AEGFRPDGFRB
SCHEMBL8400484 0.92 TUBB4A (0.58) RECQLSMN1; SMN2HIF1AEGFRPDGFRB
SCHEMBL8400485 0.92 TUBB4A (0.58) RECQLSMN1; SMN2HIF1AEGFRPDGFRB
SCHEMBL4996875 0.88 RECQL (0.67) RECQLSMN1; SMN2HIF1AEGFRPDGFRB
SCHEMBL4996892 0.88 RECQL (0.67) RECQLSMN1; SMN2HIF1AEGFRPDGFRB
SCHEMBL12507433 0.88 RECQL (0.67) RECQLSMN1; SMN2HIF1AEGFRPDGFRB
SCHEMBL8397009 0.87 NQO2 (0.75) RECQLSMN1; SMN2HIF1AEGFRPDGFRB
SCHEMBL4990755 0.87 ESR1 (0.64) RECQLSMN1; SMN2HIF1AEGFRPDGFRB
SCHEMBL8397007 0.87 NQO2 (0.75) RECQLSMN1; SMN2HIF1AEGFRPDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100435027-C Organic light receptor with charge transfer compound for electronic photographing SAMSUNG ELECTRONICS CO LTD (KR) 2008-11-19 CN disclosed
EP-1283448-B1 Electrophotographic organophotoreceptors with charge transport compounds SAMSUNG ELECTRONICS CO LTD (KR) 2008-11-05 EP disclosed
US-7358014-B2 Electrophotographic organophotoreceptors with novel charge transport compounds SAMSUNG ELECTRONICS CO., LTD. (KR) 2008-04-15 US disclosed
US-20050112490-A1 Electrophotographic organophotoreceptors with novel charge transport compounds SAMSUNG ELECTRONICS CO., LTD. 2005-05-26 US disclosed
US-20030113132-A1 Electrophotographic organophotoreceptors with novel charge transport compounds SAMSUNG INFORMATION SYSTEMS AMERICA 2003-06-19 US disclosed
CN-1410834-A Organic light receptor with charge transfer compound for electronic photographing SAMSUNG ELECTRONICS CO LTD (KR) 2003-04-16 CN disclosed
EP-1283448-A2 Electrophotographic organophotoreceptors with charge transport compounds Samsung Electronics Co., Ltd. (KR) 2003-02-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030113132-A1 Electrophotographic organophotoreceptors with novel charge transport compounds SLC43A1, SLC18A2, SLC1A1 RECQL 730/4885SMN1; SMN2 4603/4885HIF1A 3560/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.