Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1194198 | 0.88 | LTA4H (0.41) | LTA4HSIGMAR1 | |
| SCHEMBL2459174 | 0.86 | LTA4H (0.42) | LTA4HSIGMAR1 | |
| SCHEMBL2459177 | 0.86 | LTA4H (0.42) | LTA4HSIGMAR1 | |
| SCHEMBL14995124 | 0.86 | — | — | |
| SCHEMBL6133030 | 0.84 | LTA4H (0.44) | LTA4HSIGMAR1 | |
| SCHEMBL22792813 | 0.84 | LTA4H (0.44) | LTA4HSIGMAR1 | |
| SCHEMBL7021205 | 0.84 | LTA4H (0.41) | LTA4HSIGMAR1MAOB | |
| SCHEMBL1880066 | 0.84 | SIGMAR1 (0.47) | LTA4HSIGMAR1 | |
| SCHEMBL945183 | 0.84 | SIGMAR1 (0.47) | LTA4HSIGMAR1 | |
| Hydrochloric Acid SCHEMBL9674234 | 0.84 | LTA4H (0.41) | LTA4HSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296973-B1 | GUANIDINE DERIVATIVES OF QUINAZOLINE FOR USE IN THE TREATMENT OF AUTOIMMUNE DISEASES | ASTRAZENECA AB (SE) | 2008-11-05 | — | — | EP | disclosed |
| US-7001904-B1 | Guanidine derivatives quinazoline and quinoline for use in the treatment of autoimmune diseases | ASTRAZENECA AB (SE) | 2006-02-21 | — | — | US | disclosed |