⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30413055 | 1.00 | — | — | |
| SCHEMBL647114 | 0.80 | — | — | |
| SCHEMBL82304 | 0.80 | — | — | |
| Ammonia Solution, Strong SCHEMBL27508580 | 0.77 | — | — | |
| SCHEMBL31520440 | 0.77 | UHRF1 (0.41) | — | |
| Hydrochloric Acid SCHEMBL29354497 | 0.77 | HSP90AA1 (0.47) | — | |
| Ethoxycarbonyl Group SCHEMBL27709258 | 0.77 | NOS3 (0.37) | — | |
| SCHEMBL16826219 | 0.71 | FEN1 (0.46) | — | |
| SCHEMBL7921671 | 0.71 | — | — | |
| SCHEMBL1763628 | 0.70 | UHRF1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 957 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119009136-A | Pyrazinyl eutectic electrolyte with wide electrochemical stability window, and preparation method and application thereof | 中国科学院长春应用化学研究所 | 2024-11-22 | — | — | CN | claimed |
| CN-118600496-A | Electroplating solution and preparation method and application thereof | 生益电子股份有限公司 | 2024-09-06 | — | — | CN | claimed |
| CN-116143710-A | Preparation method of 2-amino-5-methylpyrazine | 苏州求索生物科技有限公司 | 2023-05-23 | — | — | CN | claimed |
| CN-113968759-A | Preparation method and application of pesticide-fertilizer granules containing amino-oligosaccharin and lythidathion | 中诚国联（河南）生物科技有限公司 | 2022-01-25 | — | — | CN | claimed |
| CN-111925333-A | Preparation method, product and application of 2-amino-5-methylpyrazine | 济南悟通生物科技有限公司 | 2020-11-13 | — | — | CN | claimed |
| US-8076481-B2 | Chemical process 632 | ASTRAZENECA AB (SE) | 2011-12-13 | — | — | US | claimed |
| CN-101857575-A | Industrial preparation method of 5-methylpyrazin-2-amine | SHANGHAI HEQUAN PHARMACEUTICAL CO LTD | 2010-10-13 | — | — | CN | claimed |
| CN-101805299-A | Benzoyl amino heterocyclyl compounds thing as glucokinase (GLK) activator | ASTRAZENECA AB | 2010-08-18 | — | — | CN | claimed |
| US-7671060-B2 | Heteroaryl benzamide derivatives | ASTRAZENECA AB (SE) | 2010-03-02 | — | — | US | claimed |
| US-20070079392-A1 | Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders | ARENA PHARMACEUTICALS, INC. (US) | 2007-04-05 | — | — | US | claimed |
| US-20050004178-A1 | Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders | ARENA PHARMACEUTICALS, INC. (US) | 2005-01-06 | — | — | US | claimed |
| US-20040142377-A1 | Human G protein-coupled receptors and modulators thereof for the treatment of metabolic-related disorders | ARENA PHARMACEUTICALS, INC. (US) | 2004-07-22 | — | — | US | claimed |
| EP-4741018-A2 | SULPHONAMIDE COMPOUNDS | Anaxis Pharma Pty Ltd (AU) | 2026-05-13 | — | — | EP | disclosed |
| EP-3571199-B1 | BICYCLIC COMPOUNDS AS ALLOSTERIC SHP2 INHIBITORS | REVOLUTION MEDICINES INC (US) | 2026-04-22 | — | — | EP | disclosed |
| EP-4142732-B1 | METHODS OF USE FOR PYRIMIDINES AS FERROPORTIN INHIBITORS | GLOBAL BLOOD THERAPEUTICS INC (US) | 2026-04-22 | — | — | EP | disclosed |
| US-20260103469-A1 | BICYCLIC COMPOUNDS AS ALLOSTERIC SHP2 INHIBITORS | REVOLUTION MEDICINES INC (US) | 2026-04-16 | — | — | US | disclosed |
| US-4133956-A | Preparation of benzoylureas | ELI LILLY AND COMPANY (US) | 1979-01-09 | — | — | US | disclosed |
| US-4083977-A | Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas | ELI LILLY AND COMPANY (US) | 1978-04-11 | — | — | US | disclosed |
| US-4042586-A | ADRENERGIC BLOCKING AGENTS | MERCK SHARP & DOHME (I.A.) CORPORATION (US) | 1977-08-16 | — | — | US | disclosed |
| US-3946009-A | ADRENERGIC BLOCKING AGENTS | MERCK SHARP & DOHME (I.A.) CORPORATION (US) | 1976-03-23 | — | — | US | disclosed |