Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 13/20 | 0.52 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclopentane SCHEMBL4695468 | 0.89 | CCR5 (0.56) | CCR5UTS2R | |
| SCHEMBL4694382 | 0.80 | SIGMAR1 (0.52) | CCR5FAAHSIGMAR1MEN1KMT2A | |
| SCHEMBL14435067 | 0.79 | CCR5 (0.53) | CCR5 | |
| Cyclopentane SCHEMBL4695436 | 0.78 | CCR5 (0.62) | CCR5 | |
| Cyclopentane SCHEMBL4695855 | 0.78 | CCR5 (0.81) | CCR5 | |
| Cyclopentane SCHEMBL4695395 | 0.78 | CCR5 (0.68) | CCR5 | |
| SCHEMBL13326659 | 0.78 | CCR5 (0.75) | CCR5 | |
| SCHEMBL13359857 | 0.78 | CCR5 (0.75) | CCR5 | |
| Cyclopentane SCHEMBL4695484 | 0.77 | CCR5 (0.78) | CCR5 | |
| Cyclopentane SCHEMBL4694741 | 0.76 | CCR5 (0.60) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |