Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 20/20 | 0.57 |
| ▸ | ITGB2 | P05107 | 19/20 | 0.57 |
| ▸ | ICAM1 | P05362 | 19/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686803 | 0.91 | ITGAL (0.57) | ITGALITGB2ICAM1 | |
| SCHEMBL4690039 | 0.90 | ITGAL (0.70) | ITGALITGB2ICAM1 | |
| SCHEMBL4686807 | 0.83 | ITGAL (0.82) | ITGALITGB2ICAM1 | |
| SCHEMBL4689932 | 0.72 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL4687022 | 0.72 | ITGAL (0.56) | ITGALITGB2ICAM1 | |
| SCHEMBL4687837 | 0.70 | ITGAL (0.40) | ITGALITGB2ICAM1 | |
| SCHEMBL6314317 | 0.70 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL6314324 | 0.70 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL5203590 | 0.69 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL5203596 | 0.69 | ITGAL (1.00) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399155-B1 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMA (US) | 2008-05-28 | — | — | EP | claimed |
| EP-1399155-A4 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMA (US) | 2004-12-15 | — | — | EP | claimed |
| EP-1399155-A2 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-03-24 | — | — | EP | claimed |
| US-6414153-B1 | TREATMENT OF INFLAMMATORY OR IMMUNE CELL-MEDIATED DISEASE OR CONDITION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-07-02 | — | — | US | claimed |
| WO-2001006984-A2 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-02-01 | — | — | WO | claimed |
| EP-1399155-B1 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMA (US) | 2008-05-28 | — | — | EP | disclosed |
| EP-1399155-B1 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMA (US) | 2008-05-28 | — | — | EP | disclosed |
| EP-1399155-A4 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMA (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1399155-A2 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2004-03-24 | — | — | EP | disclosed |
| WO-2001006984-A3 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMA (US) | 2003-12-31 | — | — | WO | disclosed |
| US-6414153-B1 | TREATMENT OF INFLAMMATORY OR IMMUNE CELL-MEDIATED DISEASE OR CONDITION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-07-02 | — | — | US | disclosed |
| US-6414153-B1 | TREATMENT OF INFLAMMATORY OR IMMUNE CELL-MEDIATED DISEASE OR CONDITION | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-07-02 | — | — | US | disclosed |
| WO-2001006984-A2 | SMALL MOLECULES USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-02-01 | — | — | WO | disclosed |