Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HCRTR1 | O43613 | 8/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4494740 | 1.00 | CCKBR (0.50) | CCKBRALOX5APFEN1KDM4EHCRTR1 | |
| SCHEMBL4693858 | 1.00 | CCKBR (0.50) | CCKBRALOX5APFEN1KDM4EHCRTR1 | |
| SCHEMBL4690394 | 0.86 | CCKBR (0.51) | CCKBRALOX5APFEN1KDM4EHCRTR1 | |
| SCHEMBL4494743 | 0.86 | CCKBR (0.51) | CCKBRALOX5APFEN1KDM4EHCRTR1 | |
| SCHEMBL4693862 | 0.86 | CCKBR (0.51) | CCKBRALOX5APFEN1KDM4EHCRTR1 | |
| SCHEMBL4694983 | 0.85 | ALOX5AP (0.43) | CCKBRALOX5APFEN1HCRTR1HCRTR2 | |
| SCHEMBL4693804 | 0.85 | ALOX5AP (0.43) | CCKBRALOX5APFEN1HCRTR1HCRTR2 | |
| SCHEMBL4692962 | 0.85 | ALOX5AP (0.43) | CCKBRALOX5APFEN1KCNK3GAA | |
| SCHEMBL4505080 | 0.85 | ALOX5AP (0.43) | CCKBRALOX5APFEN1KCNK3GAA | |
| SCHEMBL4510275 | 0.85 | ALOX5AP (0.43) | CCKBRALOX5APFEN1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651621-B1 | 2- (QUINOXALIN-5-YLSULFONYLAMINO) -BENZAMIDE COMPOUNDS AS CCK2 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-06 | — | — | EP | claimed |