Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.43 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.43 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4494743 | 1.00 | CCKBR (0.51) | CCKBRKDM4EALDH1A1TDP1ALOX5AP | |
| SCHEMBL4693862 | 1.00 | CCKBR (0.51) | CCKBRKDM4EALDH1A1TDP1ALOX5AP | |
| SCHEMBL4690393 | 0.86 | CCKBR (0.50) | CCKBRKDM4EALDH1A1ALOX5APFEN1 | |
| SCHEMBL4693858 | 0.86 | CCKBR (0.50) | CCKBRKDM4EALDH1A1ALOX5APFEN1 | |
| SCHEMBL4494740 | 0.86 | CCKBR (0.50) | CCKBRKDM4EALDH1A1ALOX5APFEN1 | |
| SCHEMBL4505084 | 0.85 | ALOX5AP (0.46) | CCKBRALOX5APFEN1HCRTR1HCRTR2 | |
| SCHEMBL4693808 | 0.85 | ALOX5AP (0.46) | CCKBRALOX5APFEN1HCRTR1HCRTR2 | |
| SCHEMBL4692965 | 0.85 | ALOX5AP (0.46) | CCKBRALOX5APFEN1HCRTR1HCRTR2 | |
| SCHEMBL4693148 | 0.85 | ALOX5AP (0.46) | CCKBRALOX5APFEN1HCRTR1HCRTR2 | |
| SCHEMBL4510279 | 0.85 | ALOX5AP (0.46) | CCKBRALOX5APFEN1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651621-B1 | 2- (QUINOXALIN-5-YLSULFONYLAMINO) -BENZAMIDE COMPOUNDS AS CCK2 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-06 | — | — | EP | claimed |