SCHEMBL469045

SCHEMBL469045

CCNC1CCS(=O)(=O)C1

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
MAPT P10636 1/20 0.52
SMN1; SMN2 Q16637 4/20 0.48
HTT P42858 3/20 0.47
LMNA P02545 2/20 0.45
GAA P10253 2/20 0.44
MAPK1 P28482 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
GLA P06280 1/20 0.41
KDM4E B2RXH2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12409575 1.00 ALDH1A1 (0.52) ALDH1A1MAPTSMN1; SMN2HTTLMNA
Hydrochloric Acid SCHEMBL21879630 0.98 ALDH1A1 (0.55) ALDH1A1MAPTSMN1; SMN2HTTLMNA
SCHEMBL15599075 0.88 ALDH1A1 (0.40) ALDH1A1MAPTSMN1; SMN2HTTLMNA
SCHEMBL12471392 0.86 ALDH1A1 (0.41) ALDH1A1MAPTSMN1; SMN2HTTLMNA
SCHEMBL23665146 0.83 HTT (0.49) ALDH1A1MAPTSMN1; SMN2HTTLMNA
SCHEMBL11199274 0.83 HTT (0.49) ALDH1A1MAPTSMN1; SMN2HTTLMNA
SCHEMBL11199747 0.82 SMN1; SMN2 (0.52) ALDH1A1MAPTSMN1; SMN2HTTLMNA
SCHEMBL11200026 0.82 SMN1; SMN2 (0.52) ALDH1A1MAPTSMN1; SMN2HTTLMNA
SCHEMBL22519413 0.81
SCHEMBL11107158 0.80 HTT (0.51) ALDH1A1MAPTSMN1; SMN2HTTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6967216-B2 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor ASTRAZENECA AB (SE) 2005-11-22 US claimed
US-20030225097-A1 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by np y5 receptor ASTRAZENECA AB (SE) 2003-12-04 US claimed
CN-122055805-A Super capacitor comprising sulfur-based electrolyte system 京瓷AVX元器件公司 2026-05-15 CN disclosed
US-20250285817-A1 Ultracapacitor for Use in a Solder Reflow Process KYOCERA AVX Components Corporation 2025-09-11 US disclosed
WO-2025085753-A1 ULTRACAPACITOR INCLUDING A SULFUR-BASED ELECTROLYTE SYSTEM KYOCERA AVX Components Corporation (US) 2025-04-24 WO disclosed
US-20250132104-A1 Ultracapacitor Including a Sulfur-Based Electrolyte System KYOCERA AVX Components Corporation 2025-04-24 US disclosed
US-20230149369-A1 Compounds that Interact with the Ras Superfamily for the Treatment of Cancers, Inflammatory Diseases, Rasopathies, and Fibrotic Disease SHY Therapeutics LLC (US) 2023-05-18 US disclosed
US-11213515-B1 Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease SHY Therapeutics LLC (US) 2022-01-04 US disclosed
US-9520617-B2 Sulfolane mixtures as ambient aprotic polar solvents ADVANCED TECHNOLOGY MATERIALS, INC. (US) 2016-12-13 US disclosed
US-20140319423-A1 SULFOLANE MIXTURES AS AMBIENT APROTIC POLAR SOLVENTS ADVANCED TECHNOLOGY MATERIALS, INC (US) 2014-10-30 US disclosed
EP-2778158-A1 Sulfolane mixtures as ambient aprotic polar solvents Advanced Technology Materials, Inc. (US) 2014-09-17 EP disclosed
US-20120065214-A1 COMPOUNDS AND THEIR USES 708 ASTRAZENECA AB (SE) 2012-03-15 US disclosed
US-7332492-B2 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor ASTRAZENECA AB (SE) 2008-02-19 US disclosed
US-6967216-B2 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor ASTRAZENECA AB (SE) 2005-11-22 US disclosed
US-20050209233-A1 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor ASTRAZENECA AB (SE) 2005-09-22 US disclosed
US-20030225097-A1 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by np y5 receptor ASTRAZENECA AB (SE) 2003-12-04 US disclosed
US-4374040-A ANTICORROSION, ANTISCALE, ANTIDERPOSIT BUCKMAN LABORATORIES, INC. (US) 1983-02-15 US disclosed
US-4243524-A ANTISCALING, ANTISLUDGING BUCKMAN LABORATORIES, INC. (US) 1981-01-06 US disclosed
US-4181806-A ANTISLUDGING AGENTS, ANTISCALING AGENTS BUCKMAN LABORATORIES, INC. (US) 1980-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050209233-A1 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by NP Y5 receptor NPY5R, NPY1R, NPY2R ALDH1A1 3658/4885MAPT 1604/4885SMN1; SMN2 1627/4885
US-20120065214-A1 COMPOUNDS AND THEIR USES 708 CYP3A7, CYP2C8, CYP2C18 ALDH1A1 340/4885MAPT 2316/4885SMN1; SMN2 4272/4885
US-20030225097-A1 Amino substituted dibenzothiophene derivatives for the treatment of disorders mediated by np y5 receptor NPY5R, NPY1R, NPY2R ALDH1A1 3792/4885MAPT 1610/4885SMN1; SMN2 1621/4885
US-11213515-B1 Compounds that interact with the Ras superfamily for the treatment of cancers, inflammatory diseases, rasopathies, and fibrotic disease HRAS, KRAS, NRAS ALDH1A1 3448/4885MAPT 4169/4885SMN1; SMN2 3555/4885
US-20230149369-A1 Compounds that Interact with the Ras Superfamily for the Treatment of Cancers, Inflammatory Diseases, Rasopathies, and Fibrotic Disease HRAS, KRAS, NRAS ALDH1A1 3448/4885MAPT 4169/4885SMN1; SMN2 3555/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.