Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 10/20 | 0.44 |
| ▸ | SCN4A | P35499 | 5/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694987 | 0.83 | GRIN2B (0.51) | CYP2D6 | |
| SCHEMBL3282848 | 0.83 | GRIN2B (0.51) | CYP2D6 | |
| SCHEMBL3285413 | 0.79 | CCR5 (0.70) | CCR5 | |
| SCHEMBL3290682 | 0.79 | CCR5 (0.70) | CCR5 | |
| Cyclopentane SCHEMBL4695436 | 0.78 | CCR5 (0.62) | CCR5 | |
| SCHEMBL4695158 | 0.77 | CCR5 (0.55) | CCR5 | |
| SCHEMBL4690351 | 0.77 | CCR5 (0.55) | CCR5 | |
| SCHEMBL4695881 | 0.76 | CCR5 (0.62) | CCR5 | |
| SCHEMBL4689791 | 0.75 | EPHX2 (0.49) | CCR5 | |
| SCHEMBL4690784 | 0.75 | CCR5 (0.68) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |