Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.51 |
| ▸ | FUCA1 | P04066 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3282848 | 1.00 | GRIN2B (0.51) | GRIN2BFUCA1HRH3CYP2D6DRD2 | |
| SCHEMBL4694382 | 0.87 | SIGMAR1 (0.52) | GRIN2B | |
| SCHEMBL4690451 | 0.83 | CCR5 (0.44) | CYP2D6 | |
| SCHEMBL13326688 | 0.83 | GRIN2B (0.50) | GRIN2B | |
| SCHEMBL3283544 | 0.81 | CYP2D6 (0.45) | GRIN2BHRH3CYP2D6 | |
| SCHEMBL4690721 | 0.81 | CCR5 (0.45) | — | |
| SCHEMBL5242542 | 0.81 | FUCA1 (0.64) | GRIN2BFUCA1HRH3DRD2DRD3 | |
| SCHEMBL4692842 | 0.81 | GBA1 (0.43) | CYP2D6 | |
| SCHEMBL18462977 | 0.80 | FUCA1 (0.51) | GRIN2BFUCA1HRH3DRD2DRD3 | |
| SCHEMBL21848108 | 0.79 | FUCA1 (0.50) | GRIN2BFUCA1TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |