Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 19/20 | 0.89 |
| ▸ | PTGER2 | P43116 | 18/20 | 0.89 |
| ▸ | PTGER3 | P43115 | 5/20 | 0.89 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.89 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4687909 | 1.00 | PTGER4 (0.89) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL4691682 | 1.00 | PTGER4 (0.89) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL4687891 | 0.94 | PTGER4 (1.00) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL4687832 | 0.94 | PTGER4 (1.00) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL11026507 | 0.94 | PTGER4 (1.00) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL4687036 | 0.94 | PTGER4 (1.00) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL11026509 | 0.94 | PTGER4 (1.00) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL4691756 | 0.92 | PTGER4 (1.00) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL4689902 | 0.92 | PTGER4 (1.00) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL4689901 | 0.92 | PTGER4 (1.00) | PTGER4PTGER2PTGER3PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603874-B1 | G-LACTAM DERIVATIVES AS PROSTAGLANDIN AGONISTS | SERONO LAB (CH) | 2008-05-07 | — | — | EP | claimed |
| US-7276531-B2 | G-lactam derivatives as prostaglandin agonists | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2007-10-02 | — | — | US | claimed |
| US-20060194865-A1 | G-lactam derivatives as prostaglandin agonists | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2006-08-31 | — | — | US | claimed |
| EP-1603874-B1 | G-LACTAM DERIVATIVES AS PROSTAGLANDIN AGONISTS | SERONO LAB (CH) | 2008-05-07 | — | — | EP | disclosed |
| US-7276531-B2 | G-lactam derivatives as prostaglandin agonists | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2007-10-02 | — | — | US | disclosed |
| US-20060194865-A1 | G-lactam derivatives as prostaglandin agonists | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (NL) | 2006-08-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060194865-A1 | G-lactam derivatives as prostaglandin agonists | PTGIS, PTGIR, PTGES | PTGER4 12/4885PTGER2 25/4885PTGER3 29/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.