Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.46 |
| ▸ | BCHE | P06276 | 6/20 | 0.46 |
| ▸ | ACHE | P22303 | 6/20 | 0.46 |
| ▸ | BACE1 | P56817 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.44 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | UBE2M | P61081 | 1/20 | 0.43 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
| ▸ | HTR1B | P28222 | 2/20 | 0.43 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16269299 | 0.81 | KDM4E (0.55) | SIGMAR1BCHEACHEBACE1KDM4E | |
| SCHEMBL28249235 | 0.79 | ACHE (0.68) | BCHEACHEBACE1CARM1PRMT6 | |
| SCHEMBL5759514 | 0.78 | BCHE (0.48) | BCHEACHEBACE1CARM1PRMT6 | |
| SCHEMBL16268490 | 0.78 | KDM4E (0.52) | SIGMAR1KDM4EALDH1A1CARM1PRMT6 | |
| SCHEMBL5560421 | 0.76 | MRGPRX1 (0.51) | SIGMAR1KDM4EALDH1A1MRGPRX1 | |
| SCHEMBL6188507 | 0.76 | MRGPRX1 (0.48) | SIGMAR1BCHEACHEBACE1KDM4E | |
| SCHEMBL3166277 | 0.75 | KDM4E (0.52) | SIGMAR1BCHEACHEBACE1KDM4E | |
| SCHEMBL8581376 | 0.75 | ACHE (0.66) | BCHEACHEBACE1CARM1PRMT6 | |
| Fumaric Acid SCHEMBL6187283 | 0.75 | SIGMAR1 (0.54) | SIGMAR1BCHEACHEBACE1KDM4E | |
| Fumaric Acid SCHEMBL6187286 | 0.75 | SIGMAR1 (0.54) | SIGMAR1BCHEACHEBACE1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638934-B1 | 3-AMINOPYRROLIDINES AS INHIBITORS OF MONOAMINE UPTAKE | LILLY CO ELI (US) | 2008-01-09 | — | — | EP | disclosed |