SCHEMBL4690718

SCHEMBL4690718

CCOC(=O)c1ccc(N2CCOCC2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.71
KMT2A Q03164 3/20 0.71
ALDH1A1 P00352 5/20 0.63
SMN1; SMN2 Q16637 5/20 0.63
RAB9A P51151 3/20 0.63
PIK3CA P42336 1/20 0.61
SIRT2 Q8IXJ6 1/20 0.61
SIRT1 Q96EB6 1/20 0.61
POLB P06746 1/20 0.60
HPGD P15428 3/20 0.58
HTT P42858 3/20 0.58
LMNA P02545 5/20 0.57
KDM4E B2RXH2 2/20 0.57
ALOX15 P16050 1/20 0.57
HSD17B10 Q99714 1/20 0.57
GSK3B P49841 2/20 0.56
MAPT P10636 3/20 0.55
MAPK1 P28482 2/20 0.55
TDP1 Q9NUW8 2/20 0.55
GAA P10253 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14871034 0.92 MEN1 (0.63) MEN1KMT2AALDH1A1SMN1; SMN2RAB9A
SCHEMBL20188098 0.90 HPGD (0.65) MEN1KMT2AALDH1A1SMN1; SMN2RAB9A
SCHEMBL22015905 0.90 HPGD (0.65) MEN1KMT2AALDH1A1SMN1; SMN2RAB9A
SCHEMBL28242074 0.87 HPGD (0.61) MEN1KMT2AALDH1A1SMN1; SMN2RAB9A
SCHEMBL3898465 0.87 HPGD (0.61) MEN1KMT2AALDH1A1SMN1; SMN2RAB9A
SCHEMBL20187714 0.86 HPGD (0.59) MEN1KMT2AALDH1A1SMN1; SMN2RAB9A
SCHEMBL3900474 0.86 SIRT2 (0.60) MEN1KMT2AALDH1A1SMN1; SMN2RAB9A
SCHEMBL6678636 0.85 SMN1; SMN2 (0.67) MEN1KMT2AALDH1A1SMN1; SMN2RAB9A
SCHEMBL6593564 0.85 MEN1 (0.55) MEN1KMT2AALDH1A1SMN1; SMN2RAB9A
SCHEMBL3457437 0.85 HPGD (0.55) MEN1KMT2AALDH1A1SMN1; SMN2RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035361-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) SHANGHAI DEGRON BIOMEDICAL TECH CO LTD (CN) 2026-02-05 US disclosed
EP-4626880-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) Shanghai Degron Biomedical Technology Co., Ltd. (CN) 2025-10-08 EP disclosed
US-12264120-B2 Amine synergists with UV—a absorption SUN CHEMICAL CORPORATION (US) 2025-04-01 US disclosed
EP-4301725-B1 AMINE SYNERGISTS WITH UV-A ABSORPTION SUN CHEMICAL CORP (US) 2024-08-21 EP disclosed
US-20240270678-A1 AMINE SYNERGISTS WITH UV-A ABSORPTION SUN CHEMICAL CORPORATION (US) 2024-08-15 US disclosed
WO-2024114639-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) SHANGHAI DEGRON BIOMEDICAL TECHNOLOGY CO., LTD. (CN) 2024-06-06 WO disclosed
EP-4301725-A1 AMINE SYNERGISTS WITH UV-A ABSORPTION Sun Chemical Corporation (US) 2024-01-10 EP disclosed
WO-2023118482-A1 AMINE SYNERGISTS WITH UV-A ABSORPTION SUN CHEMICAL CORPORATION (US) 2023-06-29 WO disclosed
WO-2023097386-A1 SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS EUROFARMA LABORATÓRIOS S.A (BR) 2023-06-08 WO disclosed
WO-2023097386-A1 SELECTIVE HDAC6-INHIBITING N-ACYLHYDRAZONE COMPOUNDS, METHODS FOR PRODUCING SAME, COMPOSITIONS, USES, TREATMENT METHODS AND KITS EUROFARMA LABORATÓRIOS S.A (BR) 2023-06-08 WO disclosed
US-20040204454-A1 Lactam-containing cyclic diamines and derivatives as factor Xa inhibitors BRISTOL-MYERS SQUIBB COMPANY 2004-10-14 US disclosed
WO-2004082687-A1 LACTAM-CONTAINING CYCLIC DIAMINES AND DERIVATIVES AS FACTOR XA INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2004-09-30 WO disclosed
WO-2004037799-A1 IMPROVEMENT IN THE STORAGE STABILITY OF PHOTOINITIATORS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-05-06 WO disclosed
US-6689882-B2 REACTING A MORPHOLINE WITH A SUBSTITUTED BENZENE, WHEREIN MORPHOLINE IS USED AS A REACTANT AND AS THE ONLY ONE SOLVENT ASTRAZENECA AB (SE) 2004-02-10 US disclosed
US-20030171581-A1 Process for the synthesis of morpholinylbenzenes ASTRAZENECA AB (SE) 2003-09-11 US disclosed
CN-1429216-A A new process for synthesis of morpholinylbenzenes ASTRAZENECA AB (SE) 2003-07-09 CN disclosed
EP-1286977-A1 A NEW PROCESS FOR THE SYNTHESIS OF MORPHOLINYLBENZENES AstraZeneca AB (SE) 2003-03-05 EP disclosed
WO-2002059132-A1 INTERMEDIATE COMPOUNDS USEFUL FOR MAKING ANTIVIRAL COMPOUNDS VIROPHARMA INCORPORATED (US) 2002-08-01 WO disclosed
WO-2001087865-A1 A NEW PROCESS FOR THE SYNTHESIS OF MORPHOLINYLBENZENES ASTRAZENECA AB (SE) 2001-11-22 WO disclosed
CN-1271279-A Amide derivatives for the treatment of diseases mediated by cytokines ZENECA LTD (GB) 2000-10-25 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12264120-B2 Amine synergists with UV—a absorption OR51E2, PNMT, ALDH7A1 MEN1 481/4885KMT2A 1548/4885ALDH1A1 11/4885
US-20240270678-A1 AMINE SYNERGISTS WITH UV-A ABSORPTION ALDH7A1, PNMT, OR51E2 MEN1 601/4885KMT2A 1208/4885ALDH1A1 8/4885
US-20040204454-A1 Lactam-containing cyclic diamines and derivatives as factor Xa inhibitors PEPD, TFPI, F2 MEN1 505/4885KMT2A 1633/4885ALDH1A1 3153/4885
US-20030171581-A1 Process for the synthesis of morpholinylbenzenes CYP1B1, TBCB, MAP1B MEN1 362/4885KMT2A 1790/4885ALDH1A1 1548/4885
US-20260035361-A1 COMPOUNDS FOR MODULATING HUR (ELAVL1) ELAVL1, ELAVL3, HNRNPL MEN1 1990/4885KMT2A 3940/4885ALDH1A1 1434/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.