Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 11/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3537801 | 0.77 | PTGER4 (0.74) | PTGER4 | |
| SCHEMBL4689944 | 0.74 | PTGER4 (0.53) | PTGER4 | |
| SCHEMBL4691571 | 0.68 | PTGER4 (0.53) | PTGER4POLBAPEX1TDP1L3MBTL1 | |
| SCHEMBL4694650 | 0.66 | PTGER4 (0.52) | PTGER4 | |
| SCHEMBL3764975 | 0.65 | PTGER4 (0.64) | PTGER4 | |
| SCHEMBL1721276 | 0.64 | MAOB (0.55) | PTGER4MAOBPARP15PARP14PARP10 | |
| SCHEMBL8435627 | 0.64 | NR4A2 (0.63) | MAOBALOX5PARP10 | |
| SCHEMBL1444784 | 0.63 | MAOB (0.75) | MAOBPARP15PARP14PARP10 | |
| SCHEMBL3541851 | 0.63 | PTGER4 (0.82) | PTGER4 | |
| SCHEMBL28752673 | 0.62 | KMT2A (0.37) | TP53L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | disclosed |