Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 12/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4691574 | 0.84 | PTGER4 (0.47) | PTGER4POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3537638 | 0.75 | PTGER4 (0.84) | PTGER4 | |
| SCHEMBL3542072 | 0.71 | PTGER4 (0.80) | PTGER4POLBNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3531262 | 0.69 | PTGER4 (1.00) | PTGER4 | |
| SCHEMBL10892168 | 0.68 | NR4A2 (0.53) | POLBNPC1RAB9ASMN1; SMN2NR4A2 | |
| SCHEMBL4690776 | 0.68 | PTGER4 (0.43) | PTGER4POLBAPEX1TDP1L3MBTL1 | |
| SCHEMBL3977567 | 0.67 | NR4A2 (0.51) | POLBNPC1RAB9ASMN1; SMN2NR4A2 | |
| SCHEMBL11464784 | 0.67 | NR4A2 (0.51) | POLBNPC1RAB9ASMN1; SMN2NR4A2 | |
| SCHEMBL4692290 | 0.66 | PTGER4 (0.71) | PTGER4 | |
| SCHEMBL4691702 | 0.66 | PTGER4 (0.59) | PTGER4POLBNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | claimed |