Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.47 |
| ▸ | RELA | Q04206 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.44 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.43 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4686959 | 0.90 | PTGER4 (0.73) | PTGER4FFAR1PPARDNR4A2 | |
| SCHEMBL3542072 | 0.85 | PTGER4 (0.80) | PTGER4RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL4687633 | 0.85 | PTGER4 (0.56) | PTGER4RAB9AFFAR1ADAMTS4 | |
| SCHEMBL4692290 | 0.77 | PTGER4 (0.71) | PTGER4 | |
| SCHEMBL3535821 | 0.74 | PTGER4 (1.00) | PTGER4MRGPRX4FFAR1PPARDNR4A2 | |
| SCHEMBL4693627 | 0.73 | PTGER4 (0.60) | PTGER4RAB9ANPC1POLBAPEX1 | |
| SCHEMBL4688386 | 0.72 | LMNA (0.57) | PTGER4PKMRXFP1L3MBTL1ALDH1A1 | |
| SCHEMBL4691574 | 0.71 | PTGER4 (0.47) | PTGER4RAB9ASMN1; SMN2NPC1POLB | |
| SCHEMBL3537874 | 0.70 | PTGER4 (0.76) | PTGER4RAB9AFFAR1ADAMTS4 | |
| SCHEMBL6223461 | 0.70 | ESR2 (0.56) | RAB9ASMN1; SMN2NPC1TP53NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603893-B1 | EP4 RECEPTOR ANTAGONISTS | ASTERAND UK LTD (GB) | 2008-05-21 | — | — | EP | claimed |