Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.56 |
| ▸ | KDM1A | O60341 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.51 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.51 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.51 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676589 | 0.73 | CHRNA7 (0.53) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL11296890 | 0.73 | CHRNA7 (0.53) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL4311896 | 0.72 | HTR2C (0.55) | CHRNA7SLC6A4 | |
| SCHEMBL4692926 | 0.72 | CHRNA7 (0.51) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL4971345 | 0.72 | CHRNA7 (0.56) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL3217359 | 0.72 | CHRNA7 (1.00) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL4689211 | 0.71 | CHRNA7 (0.64) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL2218013 | 0.71 | CHRNA7 (0.50) | CHRNA7CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9718580 | 0.70 | — | — | |
| SCHEMBL6645510 | 0.70 | CDC25B (0.49) | CHRNA7CHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339712-B1 | 3-SUBSTITUTED QUINUCLIDINES AND THEIR USE AS NICOTINIC AGONISTS | NEUROSEARCH AS (DK) | 2008-02-06 | — | — | EP | claimed |