Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.44 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.44 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9676589 | 0.74 | CHRNA7 (0.53) | CHRNA7CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL4691735 | 0.73 | CHRNA7 (0.56) | CHRNA7CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL9431123 | 0.71 | CHRNA7 (0.45) | CHRNA7CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL11296886 | 0.70 | CHRNA7 (0.61) | CHRNA7CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL4971345 | 0.70 | CHRNA7 (0.56) | CHRNA7CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL3217359 | 0.70 | CHRNA7 (1.00) | CHRNA7CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL2218013 | 0.69 | CHRNA7 (0.50) | CHRNA7CHRM2CHRM1CHRM3CHRM4 | |
| Oxalic Acid SCHEMBL9493802 | 0.68 | MEN1 (0.49) | CHRNA7CHRM1CHRM3CHRM5 | |
| SCHEMBL18204352 | 0.68 | CHRNA7 (0.53) | CHRNA7CHRM2CHRM1CHRM3CHRM4 | |
| SCHEMBL9492092 | 0.68 | CHRNA7 (0.45) | CHRNA7CHRM2CHRM1CHRM3CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4292190-A | ANTIFREEZES FOR COOLING SYSTEMS OF INTERNAL COMBUSTION ENGINES | BASF WYANDOTTE CORPORATION (US) | 1981-09-29 | — | — | US | disclosed |