Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 9/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 3/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4692014 | 0.83 | CCR5 (0.55) | CCR5 | |
| SCHEMBL4692018 | 0.83 | CCR5 (0.55) | CCR5 | |
| SCHEMBL4692011 | 0.83 | CCR5 (0.55) | CCR5 | |
| SCHEMBL4691780 | 0.82 | CCR5 (0.44) | CCR5SLC6A9 | |
| SCHEMBL5527275 | 0.78 | CCR5 (0.49) | CCR5 | |
| SCHEMBL4694443 | 0.77 | CCR5 (0.55) | CCR5SLC6A9 | |
| SCHEMBL4690751 | 0.75 | CCR5 (0.53) | CCR5SLC6A9 | |
| SCHEMBL4689957 | 0.74 | CCR5 (0.52) | CCR5SLC6A9 | |
| SCHEMBL4694351 | 0.74 | CCR5 (0.52) | CCR5SLC6A9 | |
| SCHEMBL3271118 | 0.73 | CCR5 (0.52) | CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |