Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | APAF1 | O14727 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27815550 | 0.86 | MAPT (0.43) | LMNAMAPTALOX15KMT2AKDM4E | |
| SCHEMBL28236023 | 0.85 | MAPT (0.42) | LMNAMAPTALOX15KMT2AKDM4E | |
| SCHEMBL22090221 | 0.85 | MAPT (0.42) | LMNAMAPTALOX15KMT2AKDM4E | |
| SCHEMBL7097815 | 0.83 | MAPT (0.41) | LMNAMAPTALOX15KMT2AKDM4E | |
| SCHEMBL3416368 | 0.77 | SMN1; SMN2 (0.43) | LMNAMAPTALOX15KMT2AKDM4E | |
| SCHEMBL15768011 | 0.76 | HTT (0.45) | LMNAKMT2APOLBGAAALDH1A1 | |
| SCHEMBL28234394 | 0.74 | ALDH1A1 (0.39) | LMNAMAPTALOX15KMT2AKDM4E | |
| SCHEMBL710008 | 0.73 | MAPT (0.56) | LMNAMAPTKDM4EAPAF1POLB | |
| Hydrochloric Acid SCHEMBL8048126 | 0.71 | MAPT (0.55) | LMNAMAPTKDM4EAPAF1POLB | |
| SCHEMBL18529861 | 0.71 | MAPT (0.42) | LMNAMAPTALOX15KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |
| EP-0854142-B1 | Process for the preparation of 1-alkylpyrazole-5-carboxylic esters | BAYER AG (DE) | 2002-09-18 | — | — | EP | disclosed |
| EP-0854142-A1 | Process for the preparation of 1-alkylpyrazole-5-carboxylic esters | BAYER AG (DE) | 1998-07-22 | — | — | EP | disclosed |