Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4692253 | 0.83 | LMNA (0.46) | MAPTKMT2AALOX15LMNAALDH1A1 | |
| SCHEMBL27815550 | 0.83 | MAPT (0.43) | MAPTKMT2AALOX15LMNAALDH1A1 | |
| SCHEMBL7102276 | 0.83 | ALOX5 (0.37) | MAPTKMT2ALMNAALDH1A1POLB | |
| SCHEMBL28236023 | 0.82 | MAPT (0.42) | MAPTKMT2AALOX15LMNAALDH1A1 | |
| SCHEMBL22090221 | 0.82 | MAPT (0.42) | MAPTKMT2AALOX15LMNAALDH1A1 | |
| SCHEMBL11615915 | 0.78 | KMT2A (0.52) | MAPTKMT2AALOX15LMNAALDH1A1 | |
| SCHEMBL7098893 | 0.74 | AURKA (0.40) | KMT2ALMNAALDH1A1POLBKDM4E | |
| SCHEMBL9510331 | 0.74 | POLB (0.61) | MAPTKMT2ALMNAALDH1A1POLB | |
| SCHEMBL6188814 | 0.73 | MAPT (0.52) | MAPTKMT2ALMNAALDH1A1POLB | |
| SCHEMBL28234394 | 0.71 | ALDH1A1 (0.39) | MAPTKMT2AALOX15LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091940-B1 | METHOD FOR PREPARING 1-ALKYL-PYRAZOL-5-CARBOXYLIC ACID ESTERS | BAYER AG (DE) | 2003-09-10 | — | — | EP | disclosed |