Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.57 |
| ▸ | PPARG | P37231 | 5/20 | 0.54 |
| ▸ | PPARA | Q07869 | 4/20 | 0.54 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | MARS1 | P56192 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4692571 | 0.87 | PPARG (0.57) | FAAHPPARGPPARANR1H2CYP2C9 | |
| SCHEMBL4688177 | 0.87 | PPARG (0.56) | FAAHPPARGPPARANR1H2CYP2C9 | |
| SCHEMBL4689578 | 0.87 | PPARG (0.57) | FAAHPPARGPPARANR1H2MAPT | |
| SCHEMBL4693346 | 0.86 | FAAH (0.56) | FAAHPPARGPPARANR1H2CYP2C9 | |
| SCHEMBL21607519 | 0.85 | FAAH (0.59) | FAAHNR1H2MAPTMEN1NPC1 | |
| SCHEMBL14288144 | 0.84 | FAAH (0.58) | FAAHNR1H2MAPTGAAKMT2A | |
| SCHEMBL4692489 | 0.84 | MARS1 (0.60) | PPARGPPARANPC1RAB9AMARS1 | |
| SCHEMBL17595004 | 0.79 | CYP1A2 (0.53) | CYP2C9CYP2C19MAPTMEN1NPC1 | |
| SCHEMBL4688975 | 0.78 | SMN1; SMN2 (0.58) | FAAHPPARGPPARACYP2C9CYP2C19 | |
| SCHEMBL17259268 | 0.77 | MAPT (0.47) | FAAHNR1H2MAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1685113-B1 | SUBSTITUTED PYRAZOLES AS PPAR AGONISTS | SMITHKLINE BEECHAM CORP (US) | 2008-07-30 | — | — | EP | disclosed |
| US-20080021030-A1 | Substituted Pyrazoles As Ppar Agonists | SMITHKLINE BEECHAM CORPORATION | 2008-01-24 | — | — | US | disclosed |
| US-20080021030-A1 | Substituted Pyrazoles As Ppar Agonists | SMITHKLINE BEECHAM CORPORATION | 2008-01-24 | — | — | US | disclosed |
| US-20080021030-A1 | Substituted Pyrazoles As Ppar Agonists | SMITHKLINE BEECHAM CORPORATION | 2008-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080021030-A1 | Substituted Pyrazoles As Ppar Agonists | PPARD, PPARA, PPARG | FAAH 274/4885PPARG 3/4885PPARA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.