Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 9/20 | 0.53 |
| ▸ | CCL5 | P13501 | 5/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4693061 | 0.90 | CCR5 (0.51) | CCR5CCL5ALDH1A1MEN1TSHR | |
| SCHEMBL4692082 | 0.88 | CCR5 (0.54) | CCR5CCL5MEN1TSHRKMT2A | |
| SCHEMBL4693210 | 0.88 | CCR5 (0.56) | CCR5CCL5 | |
| SCHEMBL4692783 | 0.87 | CCR5 (0.60) | CCR5CCL5KMT2A | |
| SCHEMBL4691540 | 0.86 | CCR5 (0.56) | CCR5CCL5ALDH1A1KDM4EHPGD | |
| Cyclopentane SCHEMBL4695507 | 0.83 | CCR5 (0.68) | CCR5CCL5 | |
| SCHEMBL4689575 | 0.83 | CCR5 (0.47) | CCR5CCL5ALDH1A1L3MBTL1KDM4E | |
| SCHEMBL4691437 | 0.80 | CCR5 (0.54) | CCR5CCL5 | |
| SCHEMBL4692279 | 0.80 | CCR5 (0.44) | CCR5CCL5KMT2A | |
| SCHEMBL4692063 | 0.78 | CCL5 (0.51) | CCR5CCL5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |