Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.41 |
| ▸ | CCKBR | P32239 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 2/20 | 0.37 |
| ▸ | IDH1 | O75874 | 1/20 | 0.37 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4505084 | 1.00 | ALOX5AP (0.46) | ALOX5APFEN1AAK1KCNK3CCKBR | |
| SCHEMBL4693148 | 1.00 | ALOX5AP (0.46) | ALOX5APFEN1AAK1KCNK3CCKBR | |
| SCHEMBL4693145 | 0.86 | ALOX5AP (0.43) | ALOX5APFEN1KCNK3CCKBRRAB9A | |
| SCHEMBL4692962 | 0.86 | ALOX5AP (0.43) | ALOX5APFEN1KCNK3CCKBRRAB9A | |
| SCHEMBL4505080 | 0.86 | ALOX5AP (0.43) | ALOX5APFEN1KCNK3CCKBRRAB9A | |
| SCHEMBL19253668 | 0.86 | ALOX5AP (0.42) | ALOX5APFEN1KCNK3CCKBRCA12 | |
| SCHEMBL19253601 | 0.86 | ALOX5AP (0.42) | ALOX5APFEN1KCNK3CCKBRCA12 | |
| SCHEMBL19253600 | 0.86 | ALOX5AP (0.42) | ALOX5APFEN1KCNK3CCKBRCA12 | |
| SCHEMBL4694989 | 0.85 | ALOX5AP (0.46) | ALOX5APFEN1KCNK3CCKBRCA12 | |
| SCHEMBL4690394 | 0.85 | CCKBR (0.51) | ALOX5APFEN1KCNK3CCKBRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1651621-B1 | 2- (QUINOXALIN-5-YLSULFONYLAMINO) -BENZAMIDE COMPOUNDS AS CCK2 MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2008-08-06 | — | — | EP | claimed |