Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY2R | P49146 | 2/20 | 0.51 |
| ▸ | F2R | P25116 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4694022 | 0.93 | P2RX7 (0.47) | NPY2RKMT2A | |
| SCHEMBL4691177 | 0.92 | NPY2R (0.43) | NPY2RF2RLMNAKMT2AMEN1 | |
| SCHEMBL4693167 | 0.90 | HCRTR1 (0.50) | LMNAKMT2AMEN1TP53POLB | |
| SCHEMBL4692104 | 0.90 | HCRTR1 (0.50) | NPY2RLMNAKMT2AMEN1GRIN2B | |
| SCHEMBL4692884 | 0.89 | LMNA (0.48) | LMNAKMT2AMEN1GAATP53 | |
| SCHEMBL4691903 | 0.88 | MEN1 (0.55) | NPY2RLMNAKMT2AMEN1GAA | |
| SCHEMBL4690176 | 0.88 | ABL1 (0.44) | NPY2RLMNAKMT2AMEN1TP53 | |
| SCHEMBL4693690 | 0.87 | HCRTR1 (0.51) | NPY2RF2RLMNAKMT2AMEN1 | |
| SCHEMBL4694236 | 0.87 | EPHX2 (0.44) | LMNAKMT2AMEN1GAATP53 | |
| SCHEMBL4693018 | 0.87 | NPY2R (0.47) | NPY2RPTGESGAAGRIN2BSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | claimed |
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |