Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSTO1 | P78417 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.31 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4149093 | 0.88 | MEN1 (0.33) | GSTO1 | |
| SCHEMBL4692615 | 0.85 | HDAC4 (0.32) | — | |
| SCHEMBL4138268 | 0.80 | MEN1 (0.35) | GSTO1 | |
| SCHEMBL10866253 | 0.70 | MEN1 (0.47) | GSTO1 | |
| SCHEMBL4695111 | 0.69 | MTNR1A (0.34) | MTNR1AMTNR1B | |
| SCHEMBL4693024 | 0.65 | — | — | |
| SCHEMBL3905163 | 0.65 | KMT2A (0.40) | GSTO1 | |
| SCHEMBL10243532 | 0.62 | CTSK (0.46) | — | |
| SCHEMBL4697289 | 0.61 | AKR1B1 (0.36) | — | |
| SCHEMBL4811503 | 0.60 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1569935-B1 | HETEROCYCLIC COMPOUNDS, PREPARATION METHOD THEREOF AND USE OF SAME AS MEDICAMENTS, SUCH AS ANTI-BACTERIAL MEDICAMENTS AND BETA-LACTAMASE INHIBITORS | NOVEXEL (FR) | 2008-08-20 | — | — | EP | disclosed |