Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6206640 | 0.78 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL10936575 | 0.68 | — | — | |
| SCHEMBL4690979 | 0.66 | EPHX1 (0.31) | — | |
| SCHEMBL363350 | 0.64 | — | — | |
| SCHEMBL457992 | 0.64 | L3MBTL1 (0.31) | — | |
| SCHEMBL4433591 | 0.64 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL22471599 | 0.61 | — | — | |
| SCHEMBL10699985 | 0.60 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8847151 | 0.60 | — | — | |
| SCHEMBL1670664 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521757-B1 | TRICYCLIC SPIROPIPERIDINES OR SPIROPYRROLIDINES | ASTRAZENECA AB (SE) | 2008-01-30 | — | — | EP | disclosed |