Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 19/20 | 0.53 |
| ▸ | DPP7 | Q9UHL4 | 13/20 | 0.53 |
| ▸ | DPP9 | Q86TI2 | 12/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.53 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4693374 | 1.00 | DPP4 (0.53) | DPP4DPP7DPP9DPP8RIPK1 | |
| SCHEMBL496228 | 1.00 | DPP4 (0.53) | DPP4DPP7DPP9DPP8RIPK1 | |
| Hydrochloric Acid SCHEMBL496559 | 0.99 | DPP4 (0.52) | DPP4DPP7DPP9DPP8RIPK1 | |
| SCHEMBL496083 | 0.78 | RIPK1 (0.41) | DPP4DPP7DPP9DPP8RIPK1 | |
| SCHEMBL496081 | 0.78 | RIPK1 (0.41) | DPP4DPP7DPP9DPP8RIPK1 | |
| SCHEMBL5106607 | 0.72 | CSNK1E (0.49) | — | |
| Hydrochloric Acid SCHEMBL497143 | 0.71 | CSNK1E (0.48) | — | |
| SCHEMBL269523 | 0.69 | DPP4 (0.47) | DPP4DPP7DPP9DPP8 | |
| SCHEMBL4119170 | 0.69 | MAPT (0.39) | DPP4DPP7DPP9DPP8 | |
| SCHEMBL269091 | 0.69 | MAPT (0.39) | DPP4DPP7DPP9DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910317-A1 | 1-AMINO LINKED COMPOUNDS | Eli Lilly and Company (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007015805-A1 | 1-AMINO LINKED COMPOUNDS | ELI LILLY AND COMPANY (US) | 2007-02-08 | — | — | WO | disclosed |