Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 3/20 | 0.51 |
| ▸ | REN | P00797 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ITK | Q08881 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5544726 | 0.84 | GRM1 (0.47) | GRM1 | |
| SCHEMBL4693604 | 0.81 | GRM1 (0.53) | GRM1 | |
| Hydrochloric Acid SCHEMBL4691954 | 0.77 | GRM1 (0.52) | GRM1NPC1RAB9A | |
| SCHEMBL5544676 | 0.76 | GRM1 (0.47) | GRM1NPC1RAB9AITK | |
| SCHEMBL4693608 | 0.76 | GRM1 (0.46) | GRM1ITK | |
| SCHEMBL4692984 | 0.74 | GRM1 (0.47) | GRM1 | |
| SCHEMBL5544680 | 0.73 | GRM1 (0.48) | GRM1 | |
| SCHEMBL5544673 | 0.73 | GRM1 (0.48) | GRM1 | |
| Hydrochloric Acid SCHEMBL5544773 | 0.72 | GRM1 (0.46) | GRM1NPC1RAB9AITK | |
| Hydrochloric Acid SCHEMBL4691962 | 0.71 | GRM1 (0.46) | GRM1NPC1RAB9AITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1486501-B1 | AMINOMETHYL-SUBSTITUTED THIAZOLOBENZIMIDAZOLE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2008-09-10 | — | — | EP | disclosed |