Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.48 |
| ▸ | CNR2 | P34972 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | FABP2 | P12104 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13113972 | 0.84 | CNR1 (0.47) | CNR1CNR2KMT2AATMALDH1A1 | |
| SCHEMBL3524924 | 0.81 | CNR1 (0.68) | CNR1CNR2 | |
| SCHEMBL13804784 | 0.81 | CNR1 (0.68) | CNR1CNR2 | |
| SCHEMBL4694805 | 0.81 | KMT2A (0.44) | CNR1CNR2KMT2AATMALDH1A1 | |
| SCHEMBL4689377 | 0.80 | L3MBTL1 (0.40) | CNR1CNR2KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL4693279 | 0.79 | CNR1 (0.45) | CNR1CNR2KMT2AATMALDH1A1 | |
| SCHEMBL4688668 | 0.78 | CNR1 (0.61) | CNR1CNR2KMT2AALDH1A1PPARA | |
| SCHEMBL2653467 | 0.75 | CNR1 (0.62) | CNR1CNR2ALDH1A1PPARASMN1; SMN2 | |
| SCHEMBL4691613 | 0.75 | CNR1 (0.62) | CNR1CNR2ALDH1A1PPARASMN1; SMN2 | |
| SCHEMBL4692460 | 0.74 | HPGD (0.46) | CNR1CNR2KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496838-A4 | SUBSTITUTED AMIDES | MERCK & CO INC (US) | 2008-07-02 | — | — | EP | claimed |
| EP-1496838-A2 | SUBSTITUTED AMIDES | Merck & Co., Inc. (US) | 2005-01-19 | — | — | EP | claimed |
| WO-2003077847-A2 | SUBSTITUTED AMIDES | MERCK & CO., INC. (US) | 2003-09-25 | — | — | WO | claimed |
| EP-1496838-A4 | SUBSTITUTED AMIDES | MERCK & CO INC (US) | 2008-07-02 | — | — | EP | disclosed |
| EP-1496838-A2 | SUBSTITUTED AMIDES | Merck & Co., Inc. (US) | 2005-01-19 | — | — | EP | disclosed |
| WO-2003077847-A2 | SUBSTITUTED AMIDES | MERCK & CO., INC. (US) | 2003-09-25 | — | — | WO | disclosed |