Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.44 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.37 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.37 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.37 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.37 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4692460 | 0.93 | HPGD (0.46) | KMT2AMEN1SLC6A9SLC6A5L3MBTL1 | |
| SCHEMBL4693279 | 0.90 | CNR1 (0.45) | KMT2AMEN1SLC6A9SLC6A5L3MBTL1 | |
| SCHEMBL4693928 | 0.81 | CNR1 (0.48) | KMT2ASLC6A9SLC6A5L3MBTL1ALDH1A1 | |
| SCHEMBL13113965 | 0.79 | KMT2A (0.45) | KMT2AMEN1SLC6A9SLC6A5L3MBTL1 | |
| SCHEMBL3527872 | 0.77 | CNR1 (0.60) | CNR1CNR2FDFT1 | |
| SCHEMBL13804769 | 0.77 | CNR1 (0.60) | CNR1CNR2FDFT1 | |
| SCHEMBL4689377 | 0.77 | L3MBTL1 (0.40) | KMT2AMEN1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL4689240 | 0.77 | HPGD (0.39) | KMT2AMEN1L3MBTL1ALDH1A1RAB9A | |
| SCHEMBL5266049 | 0.76 | RAB9A (0.60) | KMT2AMEN1SLC6A9SLC6A5L3MBTL1 | |
| SCHEMBL4689271 | 0.74 | RAB9A (0.48) | KMT2AMEN1L3MBTL1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1496838-A4 | SUBSTITUTED AMIDES | MERCK & CO INC (US) | 2008-07-02 | — | — | EP | claimed |
| EP-1496838-A2 | SUBSTITUTED AMIDES | Merck & Co., Inc. (US) | 2005-01-19 | — | — | EP | claimed |
| WO-2003077847-A2 | SUBSTITUTED AMIDES | MERCK & CO., INC. (US) | 2003-09-25 | — | — | WO | claimed |