Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4693180 | 0.97 | MAPK1 (0.32) | MAPK1 | |
| SCHEMBL4693875 | 0.91 | — | — | |
| SCHEMBL4695750 | 0.90 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL4694431 | 0.88 | MAPK1 (0.32) | MAPK1 | |
| SCHEMBL4692972 | 0.87 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL5233167 | 0.81 | CACNA1H (0.32) | — | |
| SCHEMBL4692912 | 0.79 | LMNA (0.30) | MAPK1 | |
| SCHEMBL4693885 | 0.76 | LMNA (0.40) | MAPK1 | |
| SCHEMBL4695789 | 0.75 | CHRM2 (0.34) | MAPK1 | |
| SCHEMBL5227482 | 0.75 | MAPK1 (0.32) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509528-B1 | 1,3-DIAZA-DIBENZOAZULENES AS INHIBITORS OF TUMOUR NECROSIS FACTOR PRODUCTION AND INTERMEDIATES FOR THE PREPARATION THEREOF | GLAXOSMITHKLINE ZAGREB (HR) | 2008-09-24 | — | — | EP | claimed |