Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.61 |
| ▸ | CNR1 | P21554 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.48 |
| ▸ | RAF1 | P04049 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.39 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17226863 | 0.84 | CNR2 (0.53) | CNR2CNR1ALDH1A1MAPK14CYP2C8 | |
| SCHEMBL469315 | 0.83 | CNR2 (0.50) | CNR2CNR1ALDH1A1MAPK14RAF1 | |
| SCHEMBL469292 | 0.77 | CNR2 (0.69) | CNR2CNR1ALDH1A1MAPK14 | |
| SCHEMBL469440 | 0.77 | CNR2 (0.62) | CNR2CNR1ALDH1A1MAPK14RAF1 | |
| SCHEMBL10217108 | 0.76 | CNR2 (1.00) | CNR2CNR1ALDH1A1MAPK14 | |
| SCHEMBL2204122 | 0.74 | CNR2 (1.00) | CNR2CNR1ALDH1A1 | |
| SCHEMBL13391625 | 0.74 | CNR2 (0.79) | CNR2CNR1ALDH1A1MAPK14IDO1 | |
| SCHEMBL13413876 | 0.74 | CNR2 (0.79) | CNR2CNR1ALDH1A1MAPK14IDO1 | |
| SCHEMBL13391462 | 0.74 | CNR2 (0.79) | CNR2CNR1ALDH1A1MAPK14IDO1 | |
| SCHEMBL15121199 | 0.74 | ALDH1A1 (0.70) | CNR2CNR1ALDH1A1MAPK14RAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595959-B1 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INT (DE) | 2015-11-04 | — | — | EP | disclosed |
| US-8846936-B2 | Sulfonyl compounds which modulate the CB2 receptor | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-09-30 | — | — | US | disclosed |
| US-20130184315-A1 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2013-07-18 | — | — | US | disclosed |
| WO-2012012307-A9 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-03-15 | — | — | WO | disclosed |
| WO-2012012307-A1 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECE | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130184315-A1 | SULFONYL COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | CNR2, CNR1, GPR52 | CNR2 1/4885CNR1 2/4885ALDH1A1 2934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.