Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CCR5 | P51681 | 13/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4690445 | 0.95 | EPHX2 (0.38) | CCR5KCNH2EPHX2 | |
| SCHEMBL4690611 | 0.95 | CCR5 (0.37) | MAPTCCR5KCNH2EPHX2UBE2M | |
| SCHEMBL4690740 | 0.94 | CCR5 (0.42) | CCR5KCNH2 | |
| SCHEMBL4694952 | 0.94 | CCR5 (0.37) | CCR5KCNH2UBE2MDCUN1D1 | |
| SCHEMBL4695361 | 0.93 | CCR5 (0.37) | CCR5KCNH2EPHX2 | |
| SCHEMBL4690521 | 0.93 | CCR5 (0.34) | CCR5KCNH2EPHX2UBE2MDCUN1D1 | |
| SCHEMBL4694017 | 0.93 | CCR5 (0.43) | CCR5KCNH2EPHX2 | |
| SCHEMBL4751512 | 0.93 | LIMK1 (0.38) | CCR5KCNH2EPHX2 | |
| SCHEMBL4690306 | 0.92 | CCR5 (0.38) | CCR5KCNH2EPHX2UBE2MDCUN1D1 | |
| SCHEMBL4691638 | 0.92 | CCR5 (0.37) | CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761542-B1 | OCTAHYDROPYRROLO[3,4-C]PYRROLE DERIVATIVES AN THEIR USE AS ANTIVIRAL AGENTS | HOFFMANN LA ROCHE (CH) | 2008-01-02 | — | — | EP | disclosed |