Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14492438 | 1.00 | TSHR (0.31) | TSHR | |
| SCHEMBL4011633 | 0.79 | TSHR (0.33) | TSHR | |
| SCHEMBL11788032 | 0.78 | ALOX15 (0.40) | — | |
| SCHEMBL19819813 | 0.78 | GABBR2 (0.33) | — | |
| SCHEMBL13559130 | 0.78 | — | — | |
| SCHEMBL14095849 | 0.77 | TSHR (0.32) | TSHR | |
| SCHEMBL14980767 | 0.76 | MEN1 (0.34) | TSHR | |
| SCHEMBL987286 | 0.76 | — | — | |
| SCHEMBL213668 | 0.75 | — | — | |
| SCHEMBL12388236 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032209-A2 | PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF DRY EYE | UNIVERSIDAD MIGUEL HERNÁNDEZ DE ELCHE (ES) | 2012-03-15 | — | — | WO | disclosed |