SCHEMBL4694986

SCHEMBL4694986

CCOC(=O)C=C(C#N)c1ccc(N(CC)CC)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 13/20 0.45
MEN1 O00255 12/20 0.45
KMT2A Q03164 12/20 0.45
ALDH1A1 P00352 12/20 0.45
MAPK1 P28482 8/20 0.45
L3MBTL1 Q9Y468 8/20 0.45
POLB P06746 6/20 0.45
LMNA P02545 5/20 0.45
USP2 O75604 2/20 0.45
RECQL P46063 2/20 0.45
BLM P54132 1/20 0.45
SMN1; SMN2 Q16637 4/20 0.42
NPC1 O15118 2/20 0.41
RAB9A P51151 2/20 0.41
HTT P42858 2/20 0.41
GAA P10253 3/20 0.40
MCL1 Q07820 1/20 0.40
NOX1 Q9Y5S8 1/20 0.40
TDP1 Q9NUW8 3/20 0.39
NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4694984 1.00 MAPT (0.45) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL4696363 0.88 ALDH1A1 (0.48) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL21457226 0.88 MAPT (0.47) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL21457758 0.87 MAPT (0.42) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL21457235 0.85 ALDH1A1 (0.42) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL10974068 0.84 SMN1; SMN2 (0.47) MAPTMEN1KMT2AALDH1A1POLB
SCHEMBL21457386 0.84 MAPT (0.44) MAPTMEN1KMT2AALDH1A1MAPK1
SCHEMBL21457569 0.83 SMN1; SMN2 (0.49) MAPTMEN1KMT2AALDH1A1POLB
SCHEMBL21457257 0.83 ESR1 (0.51) ALDH1A1MAPK1LMNASMN1; SMN2TDP1
SCHEMBL11738151 0.83 MEN1 (0.49) MAPTMEN1KMT2AALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11225540-B2 Copolymer and optical film using same TOSOH CORPORATION (JP) 2022-01-18 US disclosed
CN-110248971-B Copolymer and optical film using the same 东曹株式会社 2021-11-02 CN disclosed
US-20200095358-A1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-3553097-A1 COPOLYMER AND OPTICAL FILM USING SAME Tosoh Corporation (JP) 2019-10-16 EP disclosed
US-8754179-B2 Light activated shape memory co-polymers CORNERSTONE RESEARCH GROUP, INC. (US) 2014-06-17 US disclosed
US-20080021166-A1 Light Activated Shape Memory Co-Polymers GOVERNMENT OF THE UNITED STATES AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE 2008-01-24 US disclosed