Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GLB1 | P16278 | 1/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820952 | 0.88 | CYP19A1 (0.40) | — | |
| SCHEMBL4679652 | 0.81 | POLB (0.58) | PLGPOLB | |
| SCHEMBL4054752 | 0.77 | GLB1 (0.47) | GLB1GBA2 | |
| SCHEMBL2693506 | 0.76 | POLB (0.61) | POLB | |
| SCHEMBL6535532 | 0.76 | POLB (0.61) | POLB | |
| SCHEMBL6535590 | 0.76 | POLB (0.61) | POLB | |
| SCHEMBL27994872 | 0.76 | PLG (0.44) | PLGPOLB | |
| SCHEMBL1177524 | 0.76 | PLG (0.44) | PLGPOLB | |
| SCHEMBL5556878 | 0.75 | LTA4H (0.54) | PLGPOLBGLB1GBA2 | |
| SCHEMBL3817645 | 0.75 | LTA4H (0.54) | PLGPOLBGLB1GBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1963285-A1 | BRADYKININ 1 RECEPTOR ANTAGONISTS | Amgen Inc. (US) | 2008-09-03 | — | — | EP | disclosed |
| WO-2007067629-A1 | BRADYKININ 1 RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 2007-06-14 | — | — | WO | disclosed |