Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4696384 | 0.88 | PLG (0.43) | — | |
| SCHEMBL5254367 | 0.78 | MEN1 (0.40) | SIGMAR1 | |
| SCHEMBL29139845 | 0.78 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL4679652 | 0.78 | POLB (0.58) | — | |
| SCHEMBL5563809 | 0.77 | LTA4H (0.50) | CYP19A1SIGMAR1 | |
| SCHEMBL5558725 | 0.77 | LTA4H (0.50) | CYP19A1SIGMAR1 | |
| SCHEMBL7293928 | 0.77 | MEN1 (0.39) | CYP19A1SIGMAR1 | |
| SCHEMBL10601127 | 0.76 | POLB (0.61) | — | |
| SCHEMBL7284180 | 0.75 | SIGMAR1 (0.41) | SIGMAR1 | |
| SCHEMBL14058359 | 0.75 | POLB (0.44) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |