SCHEMBL4696428

SCHEMBL4696428

CC(=O)OC(OC(=O)C(N)C1CCC(C(=O)O)CC1)C(C)C

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.33
ANPEP P15144 1/20 0.33
ENPEP Q07075 1/20 0.33
PLG P00747 1/20 0.32
PLAT P00750 1/20 0.32
LMNA P02545 1/20 0.32
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL916330 1.00 TSHR (0.33) TSHRANPEPENPEPPLGPLAT
SCHEMBL914976 0.90 ANPEP (0.33) ANPEPENPEPPLGPLATLMNA
SCHEMBL4699309 0.90 ANPEP (0.33) ANPEPENPEPPLGPLATLMNA
SCHEMBL915925 0.87 ANPEP (0.35) ANPEPENPEPPLGPLATLMNA
SCHEMBL4697132 0.87 ANPEP (0.35) ANPEPENPEPPLGPLATLMNA
SCHEMBL914434 0.85 TSHR (0.35) TSHRANPEPENPEPPLGPLAT
SCHEMBL3257078 0.85 TSHR (0.35) TSHRANPEPENPEPPLGPLAT
SCHEMBL915446 0.85 KMT2A (0.33) ANPEPENPEPLMNAKMT2A
SCHEMBL915959 0.85 MMP1 (0.40) ANPEPENPEPPLGPLATLMNA
SCHEMBL4699450 0.83 ANPEP (0.33) ANPEPENPEPPLGPLATLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1919859-A2 ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE Xenoport, Inc. (US) 2008-05-14 EP disclosed
WO-2007002013-A2 ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE XENOPORT, INC. (US) 2007-01-04 WO disclosed