Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL915925 | 1.00 | ANPEP (0.35) | ANPEPENPEPPLGPLATLMNA | |
| SCHEMBL914994 | 0.91 | ANPEP (0.33) | ANPEPENPEPPLGPLATLMNA | |
| SCHEMBL4699450 | 0.91 | ANPEP (0.33) | ANPEPENPEPPLGPLATLMNA | |
| SCHEMBL915959 | 0.89 | MMP1 (0.40) | ANPEPENPEPPLGPLATLMNA | |
| SCHEMBL914976 | 0.88 | ANPEP (0.33) | ANPEPENPEPPLGPLATLMNA | |
| SCHEMBL4699309 | 0.88 | ANPEP (0.33) | ANPEPENPEPPLGPLATLMNA | |
| SCHEMBL924545 | 0.88 | LMNA (0.40) | ANPEPENPEPLMNA | |
| SCHEMBL4698134 | 0.88 | LMNA (0.40) | ANPEPENPEPLMNA | |
| SCHEMBL915947 | 0.87 | ANPEP (0.36) | ANPEPENPEPPLGPLATLMNA | |
| SCHEMBL916330 | 0.87 | TSHR (0.33) | ANPEPENPEPPLGPLATLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011028234-A1 | USES OF ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID | XENOPORT, INC. (US) | 2011-03-10 | — | — | WO | disclosed |
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | disclosed |