Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698373 | 0.66 | — | — | |
| SCHEMBL9351595 | 0.63 | KMT2A (0.53) | KMT2AMAPTALDH1A1 | |
| SCHEMBL4509613 | 0.60 | CYP3A4 (0.36) | KMT2AKDM4ENSD2MAPTTHRB | |
| SCHEMBL4697239 | 0.60 | ALDH1A1 (0.31) | KMT2AALDH1A1 | |
| SCHEMBL9351466 | 0.59 | KMT2A (0.31) | KMT2AKDM4ENSD2MAPTTHRB | |
| SCHEMBL9113841 | 0.59 | ALDH1A1 (0.39) | KMT2AALDH1A1 | |
| SCHEMBL7155983 | 0.56 | — | — | |
| SCHEMBL11245537 | 0.54 | CYP3A4 (0.46) | KDM4EALDH1A1 | |
| SCHEMBL1032396 | 0.54 | MEN1 (0.35) | KMT2AMAPT | |
| SCHEMBL19086522 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658099-B1 | COMPOUNDS AND KITS FOR PREPARING IMAGING AGENTS AND METHODS OF IMAGING | GEN ELECTRIC (US) | 2008-09-10 | — | — | EP | disclosed |
| EP-1658099-A1 | COMPOUNDS AND KITS FOR PREPARING IMAGING AGENTS AND METHODS OF IMAGING | General Electric Company (US) | 2006-05-24 | — | — | EP | disclosed |
| WO-2005023317-A1 | COMPOUNDS AND KITS FOR PREPARING IMAGING AGENTS AND METHODS OF IMAGING | GENERAL ELECTRIC COMPANY (US) | 2005-03-17 | — | — | WO | disclosed |
| US-20050049487-A1 | Compounds and kits for preparing imaging agents and methods of imaging | GENERAL ELECTRIC COMPANY | 2005-03-03 | — | — | US | disclosed |