Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698215 | 0.87 | LMNA (0.31) | LMNASMN1; SMN2 | |
| SCHEMBL2146900 | 0.83 | — | — | |
| SCHEMBL4697575 | 0.82 | TSHR (0.31) | — | |
| SCHEMBL4698401 | 0.78 | PPARA (0.31) | — | |
| SCHEMBL4700743 | 0.76 | DPP4 (0.32) | — | |
| SCHEMBL4700325 | 0.76 | PPARA (0.30) | — | |
| SCHEMBL10650039 | 0.76 | SMN1; SMN2 (0.44) | LMNASMN1; SMN2ALDH1A1 | |
| Acetic Acid SCHEMBL10786749 | 0.75 | SMN1; SMN2 (0.41) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4697046 | 0.74 | LMNA (0.41) | LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL4700764 | 0.74 | LMNA (0.37) | LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919859-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | Xenoport, Inc. (US) | 2008-05-14 | — | — | EP | claimed |
| WO-2007002013-A2 | ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE | XENOPORT, INC. (US) | 2007-01-04 | — | — | WO | claimed |