SCHEMBL4700743

SCHEMBL4700743

CC(C)C(=O)OC(OC(=O)C(N)C1(C(=O)O)CCCCC1)C1CCCCC1

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.32
DPP7 Q9UHL4 1/20 0.32
METAP2 P50579 2/20 0.30
METAP1 P53582 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4700775 0.84
SCHEMBL2146900 0.83
SCHEMBL4698409 0.78 PPARA (0.31)
SCHEMBL4698385 0.76
SCHEMBL4696948 0.76 LMNA (0.32)
SCHEMBL4698215 0.74 LMNA (0.31)
SCHEMBL4697575 0.73 TSHR (0.31)
SCHEMBL4698314 0.73 DPP4 (0.37) DPP4DPP7
SCHEMBL916672 0.73 DPP4 (0.37) DPP4DPP7
SCHEMBL4696638 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1919859-A2 ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE Xenoport, Inc. (US) 2008-05-14 EP claimed
WO-2007002013-A2 ACYLOXYALKYL CARBAMATE PRODRUGS OF TRANEXAMIC ACID, METHODS OF SYNTHESIS AND USE XENOPORT, INC. (US) 2007-01-04 WO claimed