Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.53 |
| ▸ | MALT1 | Q9UDY8 | 10/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4697505 | 0.86 | MALT1 (0.48) | HRH3MALT1KMT2AKDM4ERECQL | |
| SCHEMBL22598170 | 0.83 | GRIN2D (0.48) | HRH3MALT1KMT2A | |
| SCHEMBL4533155 | 0.82 | MALT1 (0.54) | MALT1KMT2AKDM4ERECQL | |
| SCHEMBL4696957 | 0.81 | ALDH1A1 (0.59) | HRH3 | |
| SCHEMBL14377345 | 0.80 | MALT1 (0.49) | MALT1KMT2A | |
| SCHEMBL14334510 | 0.77 | MALT1 (0.60) | MALT1KMT2AKDM4ERECQL | |
| SCHEMBL3202936 | 0.76 | GRIN2D (0.45) | HRH3MALT1KMT2AKDM4ERECQL | |
| SCHEMBL22587546 | 0.76 | PIK3CA (0.46) | HRH3MALT1KMT2AKDM4ERECQL | |
| SCHEMBL29445480 | 0.76 | PIK3CA (0.46) | HRH3MALT1KMT2AKDM4ERECQL | |
| SCHEMBL10278269 | 0.76 | GRIN2D (0.42) | HRH3MALT1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1603895-B1 | SUBSTITUTED BENZOYLUREIDOPYRIDYL-PIPERIDINE AND -PYRROLIDINE CARBOXYLIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THE USE THEREOF | SANOFI AVENTIS DEUTSCHLAND (DE) | 2008-02-20 | — | — | EP | disclosed |
| EP-1603895-A1 | SUBSTITUTED BENZOYLUREIDOPYRIDYL-PIPERIDINE AND -PYRROLIDINE CARBOXYLIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THE USE THEREOF | Sanofi-Aventis Deutschland GmbH (DE) | 2005-12-14 | — | — | EP | disclosed |
| WO-2004078743-A1 | SUBSTITUTED BENZOYLUREIDOPYRIDYL-PIPERIDINE AND -PYRROLIDINE CARBOXYLIC ACID DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THE USE THEREOF | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-09-16 | — | — | WO | disclosed |