Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.66 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4513535 | 0.83 | GPR119 (0.72) | GPR119TGFBR1MEN1KMT2A | |
| SCHEMBL4518371 | 0.83 | GPR119 (0.66) | GPR119 | |
| SCHEMBL4514525 | 0.82 | GPR119 (0.74) | GPR119TGFBR1MEN1KMT2A | |
| SCHEMBL4520117 | 0.82 | GPR119 (0.71) | GPR119TGFBR1MEN1KMT2A | |
| SCHEMBL4512522 | 0.81 | GPR119 (0.70) | GPR119MEN1KMT2A | |
| SCHEMBL3923864 | 0.81 | GPR119 (0.79) | GPR119MEN1KMT2A | |
| SCHEMBL4511917 | 0.81 | GPR119 (0.66) | GPR119 | |
| SCHEMBL3486452 | 0.80 | GPR119 (1.00) | GPR119 | |
| SCHEMBL4516831 | 0.80 | GPR119 (0.74) | GPR119 | |
| SCHEMBL4516005 | 0.80 | GPR119 (0.67) | GPR119TGFBR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1909791-A1 | G-PROTEIN COUPLED RECEPTOR AGONISTS | Prosidion Limited (GB) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007003964-A1 | G-PROTEIN COUPLED RECEPTOR AGONISTS | PROSIDION LIMITED (GB) | 2007-01-11 | — | — | WO | disclosed |