Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP4 | P15090 | 1/20 | 0.48 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9404382 | 0.91 | FABP4 (0.47) | FABP4FABP5CA12CA1CA2 | |
| SCHEMBL6400516 | 0.85 | KMT2A (0.55) | FABP4FABP5CA12CA1CA2 | |
| SCHEMBL503436 | 0.85 | KMT2A (0.55) | FABP4FABP5CA12CA1CA2 | |
| SCHEMBL503435 | 0.85 | KMT2A (0.55) | FABP4FABP5CA12CA1CA2 | |
| SCHEMBL4699670 | 0.84 | AOC3 (0.50) | CA12CA1CA2CA7CA9 | |
| SCHEMBL490689 | 0.83 | PTGS1 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11081241 | 0.83 | CA12 (0.47) | FABP4FABP5CA12CA1CA2 | |
| SCHEMBL3082625 | 0.83 | CA1 (0.46) | FABP4FABP5CA12CA1CA2 | |
| SCHEMBL2461230 | 0.83 | KDM4E (0.50) | FABP4FABP5CA12CA1CA2 | |
| SCHEMBL2461228 | 0.83 | KDM4E (0.50) | FABP4FABP5CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110483264-A | A kind of synthetic method of veratraldehyde | SHANDONG NHU PHARMACEUTICAL CO LTD | 2019-11-22 | — | — | CN | disclosed |
| CN-110483264-A | A kind of synthetic method of veratraldehyde | SHANDONG NHU PHARMACEUTICAL CO LTD | 2019-11-22 | — | — | CN | disclosed |
| EP-1931636-A1 | ISOQUINOLINES AS IGF-1R INHIBITORS | Analytecon S.A. (CH) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007029106-A1 | ISOQUINOLINES AS IGF-1R INHIBITORS | ANALYTECON SA (CH) | 2007-03-15 | — | — | WO | disclosed |